Monday, January 25, 2010

Recent Review: RNAi Routes to Studying Aging


Another paper on my desk today--a mini-review on using RNAi screens, such as in
C. elegans and in vivo in flies, to study aging.

Minois et al (2010). RNA Interference in Ageing Research - A Mini-Review. Gerontology. PubMed PMID: 20090308.

Related Links (resources for in vivo RNAi in Drosophila):

Trendy Science? Acai Berries & Fruit Flies

Even Drosophila research is being influenced by the trends--here's a paper on the effects of acai berries in the context of a high-fat diet. Sun et al. (2010) A├žai Palm Fruit (Euterpe oleracea Mart.) Pulp Improves Survival of Flies on a High Fat Diet. Exp Gerontol. PubMed PMID: 20080168.

Friday, January 22, 2010

Breaking Report: in vivo RNAi screen on obesity

What's on my desk today? (And okay, I admit, it has been on my desk for several days ... busy times):

Pospisilik et al (2010). Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate. Cell. Jan 8;140(1):148-60. PubMed PMID: 20074523.

Monday, January 11, 2010

Breaking Report: Tiling Arrays to Deconvolve shRNA Pools

What am I reading today? Report of a technical development in the 'mammalian world' of RNAi screening.

Boettcher et al. (2010) Decoding pooled RNAi screens by means of barcode tiling arrays. BMC Genomics. 2010 Jan 5;11(1):7.