Breaking Report: Power of Combinatorial RNAi

On my desk to read today? A new report from T. Horn and colleagues in the Boutros group on the use of double-knockdown to uncover genetic interactions.

Horn et al. (2011) Mapping of signaling networks through synthetic genetic interaction analysis by RNAi. Nature Methods. Advanced online publication. PMID: 21378980.

More than 70,000 measurements!