Thursday, June 18, 2015

miRNA "sponge" fly stock resource

Fulga TA, McNeill EM, Binari R, Yelick J, Blanche A, Booker M, Steinkraus BR, Schnall-Levin M, Zhao Y, DeLuca T, Bejarano F, Han Z, Lai EC, Wall DP, Perrimon N, Van Vactor D. A transgenic resource for conditional competitive inhibition of conserved Drosophila microRNAs. Nat Commun. 2015 Jun 17;6:7279. PMID: 26081261.

From the abstract: "... Development of competitive inhibitor molecules such as miRNA sponges has allowed the community to address individual miRNA function in vivo. ... Here we offer a comprehensive library of 141 conditional miRNA sponges targeting well-conserved miRNAs in Drosophila. ..."

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